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Cell biology at the molecular level
We are interested in two processes fundamental to eukaryotic cellular life: mitosis and membrane trafficking. We want to understand how these processes operate at the molecular level to prevent diseases such as cancer, cardiovascular and neurodegenerative diseases.
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Méghane and Steve tracked vesicles zooming around inside cells and found that diffusion is the main mode of nanovesicle transport.
>> Sittewelle & Royle (2023)
| [Paper] | [Plain English]
Old news is good news
Browse or search our lab news and events Twitter archive from before 2022.
Life is the (mito)pits
Cansu and others show that clathrin-coated pits can be made to form inside cells. Even on mitochondria! This work reveals what are the essential ingredients to cook up a vesicle.
>> Küey et al. (2022)
Lost in membranes
Nuria, Laura and George show how endomembranes can cause chromosome missegregation in mitosis.
>> Ferrandiz et al. (2022)
| [Paper] | [Plain English] [Spotlight]
See all of our papers here