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Current Lab Members


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        STEPHEN ROYLE
        I'm interested in things that cells do: how they move proteins around, how they divide and how they move. I did my undergrad at University of Sheffield and my PhD in the Department of Pharmacology at University of Cambridge. Next I did a post-doc with Leon Lagnado at the MRC Laboratory of Molecular Biology and started my own group in 2006/7 at Liverpool, moving the lab to Warwick in 2013.
        Besides being PI, my role in the lab is doing programming and data analysis in collaboration with everyone in the group.

        ORCiD: <a href='http://orcid.org/0000-0001-8927-6967'>0000-0001-8927-6967</a>
        GitHub: <a href='https://github.com/quantixed'>quantixed</a>
        Twitter: <a href='https://twitter.com/clathrin'>@clathrin</a>
        quantixed: <a href='https://quantixed.org/'>Link</a>
        Steve Royle
Principal Investigator

        NURIA FERRÁNDIZ
        I am primarily a molecular and cellular biologist with a strong biochemistry and pharmacology background. Throughout my career I have expanded my knowledge in the area of genomic instability and chromosome biology in Mitosis and Meiosis field.
        During my PhD in Professor Javier Leon Laboratory at the Institute of Biomedicine and Biotechnology (IBBTEC), I delivered a previously uncharacterised non-cell cycle role for a known tumour suppressor protein in mammalian cellular models. For my postdoctoral training in Dr Martinez-Perez laboratory at Imperial College, I have elucidated the mechanisms that promote correct chromosome segregation during oogenesis in multicellular organisms. Currently, I am working in Dr Steve Royle laboratory at Warwick University, in a project investigating how unaligned chromosomes in mitosis are ensheathed in membrane, phenomenon that potentially could change the way we think about mechanism underlying aneuploidy during tumour cell progression.

        KEY WORDS: Mitosis, Meiosis, Chromosome segregation, Anueploidy, Spindle Assembly Checkpoint, Ensheathing chromosomes, Human Sterility and Tumour cells
        ORCiD: <a href='https://orcid.org/0000-0002-7410-3470'>0000-0002-7410-3470</a>
        ResearcherID: <a href='http://www.researcherid.com/rid/V-4071-2017'>V-4071-2017</a> Nuria Ferrándiz Díaz
Postdoc

        ELLIS RYAN
        I am a trained cell biologist interested in mitosis and genome instability. I completed my PhD at the School of Cancer Sciences at the University of Birmingham where I characterised a protein previously unknown for its roles in the regulation of the cell cycle and genome instability.
        I joined Steve’s lab as a postdoctoral researcher in September 2016. In my current role I am interested in characterising proteins that stabilise the mitotic spindle using a combination of CRISPR, light and electron microscopy.
        I am also passionate about public engagement and like to involve myself in science communication whenever I can.

        ORCiD: <a href='https://orcid.org/0000-0001-7426-2036'>0000-0001-7426-2036</a>
        Twitter: <a href='https://twitter.com/ellislouiseryan'>@ellislouiseryan</a> Ellis Ryan
Postdoc

        MÉGHANE SITTEWELLE
        I joined the team of Prof Steve Royle to study the role of TPD52-like proteins, markers of intracellular nanovesicles (INVs), in membrane trafficking and cell migration.
        Prior to that, I completed my PhD in Pr Anne-Hélène Monsoro-Burq’s lab at Institut Curie in France during which I investigated a non-canonical role of a glycolytic enzyme on cell signalling and cell migration, in both context of human melanoma cells and amphibian neural crest development.
        Before this, I did my undergraduate study in cell biology and development at the University of Paris-Saclay.

        ORCiD: <a href='https://orcid.org/0000-0002-9383-6653'>0000-0002-9383-6653</a> Méghane Sittewelle
Postdoc

        LAURA DOWNIE
        I am a PhD student on the BBSRC-funded Midlands Integrative Biosciences Training Partnership (MIBTP) programme. I am interested in mitosis and I am looking at chromosome missegregation during cell division.
        Previously, I have received BSc Molecular & Cellular Biology (with Biotechnology) from the University of Glasgow, completing an investigation into cellular response to surface topography in my final year. I then continued study at the University of Glasgow, completing a Master of Research degree, during which I investigated the possible interaction of a cell cycle regulator with a structural protein in fission yeast cytokinesis, and also the potential of specific stickleback populations as evolutionary mutant models of diabetes.

        ORCiD: <a href='https://orcid.org/0000-0001-9039-942X'>0000-0001-9039-942X</a> Laura Downie
PhD Student

        MARY FESENKO
        I am a PhD student working on membrane trafficking in the lab. Specifically, I am investigating the formation of Intracellular Nanovesicles (INVs) and their involvement in autophagy related trafficking, in collaboration with the lab of Dr Darius Koester, which is also based at the CMCB. My PhD research is funded through the MRC-DTP (Medical Research Council Doctoral Training Programme in Interdisciplinary Biomedical Research).
        I completed my undergraduate degree in Biological Sciences at the University of Oxford. There, I worked in the lab of the late Dr Ian Moore, who inspired my interest in the dynamic and self-organising properties of the eukaryotic endomembrane system, which continues to motivate my research efforts.
        I then pursued an MPhil degree at the lab of Dr Richard Hayward, based in Department of Pathology at the University of Cambridge, where I studied how the intracellular pathogen Chlamydia trachomatis hijacks the host’s membrane trafficking and the cytoskeletal organisation.

        ORCiD: <a href='https://orcid.org/0000-0002-0407-6374'>0000-0002-0407-6374</a>
        Twitter: <a href='http://twitter.com/MAFesenko/'>@MAFesenko</a> Mary Fesenko
PhD Student

        SAHIL KAMBOJ
        I am a EUTOPIA co-tutelle doctoral student who’s working on the modulation of integrins a5b1 on the surface of ovarian cancer cells to study its effects on the cancer microenvironment.
        My project is between Ambroise Lambert and Olivier Gallet at Paris Cergy U and the Royle lab in Warwick.
        Sahil Kamboj
PhD Student

        DANIEL MOORE
        I’m a PhD student on the Medical Research Council Doctoral Training Partnership in Interdisciplinary Biomedical Research Programme.

        I am interested intracellular membrane trafficking. My project involves proteins of the Tumor Protein D52 family and intracellular trafficking. My previous mini-project was developing quantitative methods to measure cortical actin during macropinocytosis.

        Before Warwick I completed a BSc at the University of York in Biomedical Sciences, with my final year project characterising the role of the ubiquitous mammalian membrane protein cellugyrin. I also undertook two summer studentships with the Cambridge Institute of Medical Research and Cancer Research UK Cambridge studying cytotoxic T cell killing.

        ORCiD: <a href='https://orcid.org/0000-0003-1553-0939'>0000-0003-1553-0939</a> Daniel Moore
PhD Student

        ALEX MOORE
        I am a research assistant doing cell line engineering in the Royle Lab. Alex Moore
Research Assistant

        JOE PARHAM
        I’m an mBio student working on methods to change the localisation of cellular compartments in interphase and mitotic cells.
        Joe Parham
Masters Student

        RYAN HARRISON
        I am doing a mini-project in the lab working on correlative light-electron microscopy tags to visualise cellular compartments.
        Ryan Harrison
Masters Student

        LAURA COOPER
        I am a Research Fellow in Computing and Image Analysis working in CAMDU, the Computing and Advanced Microscopy Unit.
        My role is to support image analysis in Biomedical Sciences at Warwick Medical School and maintain research computing infrastructure such as our OMERO database and our ELNs.

        <a href='https://warwick.ac.uk/fac/sci/med/research/biomedical/facilities/camdu/'>CAMDU</a> Laura Cooper
Honorary Member