centre for mechanochemical cell biology
our work asks about biophysical and cell-biological
mechanisms of motorized self-organization in cells.
more here
Build it up, tear it down
Muriel & Doug show that S. pombe kinesins-8 promote both microtubule nucleation and microtubule catastrophe
>> PLoS ONE (2011) Accepted Dec 23.
| e-print shortly
Electra glide
Dana & Barry report evidence that kinesin is guided to its binding site by an electrostatic force field
>> PLoS Biology (2011)
| e-print
Eg timer
Kase shows that cells that successfully separate their centrosomes in prophase make fewer errors in mitosis
>> Biology Open (2011) | e-print
Spindle centricity
Catarina and Binyam show how MAP4 and CLASP1 keep spindles in the right place during mitosis
>> Nature Cell Biology, 13 1040-1050 2011 | e-print
Dancing partners
We reveal the kinetochore components involved in coordinating microtubule dynamics
>> Nature Cell Biology, 12 319-329 2010 | e-print
Keeping track!
along with the Danuser, Swedlow and Meraldi labs we automatically track sister kinetochores in metaphase
>> Journal of Cell Biology, 188 665-79 2010 | e-print
How the CMCB came to be
Jan 2010 | The idea for the CMCB had a lengthy gestation, but then was born quite suddenly > more here
Jun 2011 | Rob's article for the BSCB (British Society for Cell Biology) about setting up the CMCB. > more here
The new CMCB building
Jan 2012 | The new 6.6M WMS Centre for Mechanochemical Cell Biology (CMCB) building is due for completion in February 2012. > more here (and here)
Microtubule Dynamics Book
July 2011 | Microtubule Dynamics: Methods and Protocols is available for pre-order. The book, edited by Anne, features chapters authored by several CMCB members, amongst them the long waited-for pombe tubulin prep protocol... > more here
>> IMAGE FACTORY | The CMCB hosts a collection of microscopes providing a range of imaging techniques from live-cell imaging to single molecule mechanical recordings. Find out more about the microscopes and how to use them here
>> Thu 19 Jan 2012 | Dr Frauke Hussmann
>> Thu 19 Jan 2012 | Anna Akhmanova: Friends at the Ends
>> Mon 16 Jan 2012 | Rob discusses "World's Smallest Motors" at a really quite good Cafe Scientific talk ...
>> Tues 6 Dec 2011 | The WOSM is coming ...
>> Tues 6 Dec 2011 | CMCB building coming along nicely
>> Wed 26 Oct 2011 | Binyam Mogessie PhD
>> Wed 26 Oct 2011| Andreas Merdes (CNRS Toulouse)
>> Wed 20 Oct 2011 | First annual CMCB retreat @ Stratford YHA
>> Wed 5 Oct | Stephen Royle (University of Liverpool)
Inter-microtubule bridges in kinetochore fibres of the mitotic spindle
>> Wed 28 Sept 2011 | Andrew Fry (University of Leicester)
Centrosome regulation through the cell cycle
>> Wed 07 Sept 2011 | Jason Swedlow (University of Dundee)
Signalling and mechanics at the human mitotic centromere and kinetochore
The University of Warwick, Coventry, CV4 7AL, United Kingdom.
